It’s the nation’s seventh most-populous city—and the fastest-growing one. It’s welcoming 66 new residents each day and is on pace to receive 1 million new arrivals in the next 25 years. Downtown, a $57 million, state-of-the art school of data science will soon open, one of a score of pivotal developments reshaping the city’s core.

Few would likely guess that the above refers to San Antonio, Texas, the state’s second-largest city—and one of the U.S.’s least understood. As this capital of Mexican-American culture celebrates its 300th birthday, it also confronts a sizable shift in its character, economy, and ambitions.

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